免疫原
Synthesized peptide derived from human KLF3 AA range: 51-101
特异性
This antibody detects endogenous levels of KLF3 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:Binds to the CACCC box of erythroid cell-expressed genes. May play a role in hematopoiesis.,PTM:Sumoylated by SUMO1. Sumoylation is enhanced by PIAS1, PIAS2alpha and PIAS2beta, and PIAS4, but not by Pc2. Enhances transcriptional repression, but has no effect on DNA binding. Sumoylation on Lys-198 is the major site.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Monomer.,
基因名称(Gene Name)
KLF3 BKLF
Fields
>>Transcriptional misregulation in cancer