免疫原
Synthesized peptide derived from human HSF2B AA range: 201-251
特异性
This antibody detects endogenous levels of HSF2B at Human
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
HSF2 binding protein (HSF2BP) associates with HSF2. The interaction occurs between the trimerization domain of HSF2 and the amino terminal hydrophilic region of HSF2BP that comprises two leucine zipper motifs. HSF2BP may therefore be involved in modulating HSF2 activation. [provided by RefSeq, Jul 2008],
功能
function:May be involved in modulating HSF2 activation in testis.,PTM:Sumoylated by UBE2I in response to MEKK1-mediated stimuli.,subunit:Associates with HSF2. The interaction seems to occur between the trimerization domain of HSF2 and the N-terminal hydrophilic region of HSF2BP.,tissue specificity:Testis specific.,
细胞定位
Cytoplasm . Chromosome . Localizes on double-strand breaks (DSBs) in mitotic and meiotic chromosomes. .
组织表达
Testis specific. Overexpressed in some tumors (PubMed:31242413).
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