免疫原
Synthesized peptide derived from human NUDT9 AA range: 107-157
特异性
This antibody detects endogenous levels of NUDT9 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
功能
catalytic activity:ADP-ribose + H(2)O = AMP + D-ribose 5-phosphate.,cofactor:Magnesium.,cofactor:Manganese.,function:Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'-phosphate.,induction:Isoform 1 is inhibited by fluoride and N-acetyl-p-benzoquinoneimine.,similarity:Belongs to the Nudix hydrolase family. NudF subfamily.,subunit:Monomer. Interacts with C17orf25.,tissue specificity:Ubiquitously expressed but isoform 1 is the most predominant isoform.,
基因名称（Gene Name）
NUDT9 NUDT10 PSEC0099 UNQ3012/PRO9771
Fields
>>Purine metabolism;>>Metabolic pathways
细胞定位
[Isoform 1]: Mitochondrion.
组织表达
Ubiquitously expressed but isoform 1 is the most predominant isoform.
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