免疫原
Synthesized peptide derived from human PI42C AA range: 262-312
特异性
This antibody detects endogenous levels of PI42C at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
catalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.,function:May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum.,PTM:Phosphorylated.,similarity:Contains 1 PI5K domain.,subcellular location:Mostly found in the cytosol and surrounding plasma membrane. However, its presence in the endoplasmic reticulum seems to be a prerequisite for PIP2 synthesis.,
基因名称(Gene Name)
PIP4K2C PIP5K2C
Fields
>>Inositol phosphate metabolism;>>Metabolic pathways;>>Phosphatidylinositol signaling system;>>Regulation of actin cytoskeleton
细胞定位
Endoplasmic reticulum . Cytoplasm .