免疫原
Synthesized peptide derived from human AFAF AA range: 223-273
特异性
This antibody detects endogenous levels of AFAF at Human
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:Involved in acrosome biogenesis.,tissue specificity:Isoform 1 highly expressed in testis. Isoform 2 is expressed at low levels in skin and blood.,
基因名称(Gene Name)
AFAF C9orf11
细胞定位
Cytoplasmic vesicle, secretory vesicle, acrosome membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, secretory vesicle, acrosome outer membrane ; Single-pass type I membrane protein . In the anterior acrosome region, enriched on the inner acrosomal membrane but minimal on the outer acrosomal membrane; in contrast in the posterior acrosome region enriched on both the inner and outer acrosomal membranes. .
组织表达
Isoform 1 is highly expressed in testis. Isoform 2 is expressed at low levels in skin and blood.