免疫原
Synthesized peptide derived from human CISY AA range: 272-322
特异性
This antibody detects endogenous levels of CISY at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
The protein encoded by this gene is a Krebs tricarboxylic acid cycle enzyme that catalyzes the synthesis of citrate from oxaloacetate and acetyl coenzyme A. The enzyme is found in nearly all cells capable of oxidative metablism. This protein is nuclear encoded and transported into the mitochondrial matrix, where the mature form is found. [provided by RefSeq, Jul 2008],
功能
catalytic activity:Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.,miscellaneous:Citrate synthase is found in nearly all cells capable of oxidative metabolism.,online information:Citrate synthase entry,pathway:Carbohydrate metabolism; tricarboxylic acid cycle.,sequence caution:Intron retention.,similarity:Belongs to the citrate synthase family.,subunit:Homodimer.,
Fields
>>Citrate cycle (TCA cycle);>>Glyoxylate and dicarboxylate metabolism;>>Metabolic pathways;>>Carbon metabolism;>>2-Oxocarboxylic acid metabolism;>>Biosynthesis of amino acids
细胞定位
Mitochondrion matrix.