免疫原
Synthesized peptide derived from human KLHL2 AA range: 521-571
特异性
This antibody detects endogenous levels of KLHL2 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:May play a role in organizing the actin cytoskeleton of the brain cells.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 Kelch repeats.,subunit:Binds actin.,tissue specificity:Predominantly expressed in brain.,
细胞定位
Cytoplasm, cytoskeleton. Cell projection, ruffle. Cell projection . Cell projection, lamellipodium . Cytoplasm, cytosol. A proportion colocalizes with the actin cytoskeleton. When over-expressed, colocalizes with NPTXR in perinuclear aggresomes (By similarity). .
组织表达
Ubiquitous. Detected throughout the brain.