免疫原
Synthesized peptide derived from human TRI66 AA range: 608-658
特异性
This antibody detects endogenous levels of TRI66 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:May function as transcription repressor; The repressive effects are mediated, at least in part, by recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through CBX3 complex formation and centromere association.,similarity:Contains 1 bromo domain.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 2 B box-type zinc fingers.,subcellular location:Forms discrete foci within the centromeric chromocenter and surrounding nucleoplasm.,subunit:Can form homo- and heterodimers. Interacts with CBX5, CBX1 and CBX3 via PxVxL motif.,
基因名称(Gene Name)
TRIM66 C11orf29 KIAA0298
细胞定位
Nucleus. Forms discrete foci within the centromeric chromocenter and surrounding nucleoplasm. .