免疫原
Synthesized peptide derived from human BAZ1A AA range: 736-786
特异性
This antibody detects endogenous levels of BAZ1A at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
The BAZ1A gene encodes the accessory subunit of the ATP-dependent chromatin assembly factor (ACF), a member of the ISWI ('imitation switch') family of chromatin remodeling complexes (summarized by Racki et al., 2009 [PubMed 20033039]).[supplied by OMIM, Apr 2010],
功能
function:May play a role in transcriptional regulation. May be involved in the formation or maintenance of heterochromatin playing a critical role in developmental control.,miscellaneous:Stimulated by double-stranded DNA and nucleosomal DNA.,similarity:Belongs to the WAL family.,similarity:Contains 1 bromo domain.,similarity:Contains 1 DDT domain.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 WAC domain.,subcellular location:May target the CHRAC complex to heterochromatin.,subunit:Together with CHRAC1, POLE3 and SMARCA5 proteins, it forms the ISWI chromatin-remodeling complex, CHRAC.,tissue specificity:Highly expressed in testis and at low or undetectable levels in other tissues analyzed.,
基因名称（Gene Name）
BAZ1A ACF1 WCRF180 HSPC317
细胞定位
Nucleus. May target the CHRAC complex to heterochromatin.
组织表达
Highly expressed in testis and at low or undetectable levels in other tissues analyzed.
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