免疫原
Synthesized peptide derived from human LRC3B AA range: 115-165
特异性
This antibody detects endogenous levels of LRC3B at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
The protein encoded by this gene is a tumor suppressor, with lowered expression levels found in gastric, renal, colorectal, lung, and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues, although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015],
功能
similarity:Belongs to the LRRC3 family.,similarity:Contains 3 LRR (leucine-rich) repeats.,
基因名称(Gene Name)
LRRC3B LRP15 UNQ195/PRO221
细胞定位
Membrane ; Single-pass membrane protein .