免疫原
Synthesized peptide derived from human APBB3 AA range: 403-453
特异性
This antibody detects endogenous levels of APBB3 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
功能
function:May modulate the internalization of beta-amyloid precursor protein.,similarity:Contains 1 WW domain.,similarity:Contains 2 PID domains.,subunit:Binds to the intracellular domain of the beta-amyloid precursor protein. Also bind to APP-like proteins.,tissue specificity:Expressed in various tissues.,
基因名称（Gene Name）
APBB3 FE65L2
细胞定位
Cytoplasm . Nucleus .; [Isoform I-214]: Nucleus.; [Isoform I-245]: Nucleus.
组织表达
Expressed in various tissues, highest expression in brain.
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