免疫原
Synthesized peptide derived from human Beta-defensin 4A AA range: 1-50
特异性
This antibody detects endogenous levels of human Beta-defensin 4A
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:50-200, ELISA(peptide)1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
背景(Background)
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Jul 2008],
功能
function:Has antibacterial activity .,induction:By inflammation.,similarity:Belongs to the beta-defensin family. LAP/TAP subfamily.,tissue specificity:Expressed in the skin and respiratory tract.,
基因名称(Gene Name)
DEFB4A DEFB102 DEFB2 DEFB4; DEFB4B
其他名称
Beta-defensin 4A (Beta-defensin 2;BD-2;hBD-2;Defensin, beta 2;Skin-antimicrobial peptide 1;SAP1)
Fields
>>NOD-like receptor signaling pathway;>>IL-17 signaling pathway;>>Staphylococcus aureus infection
组织表达
Expressed in the skin and respiratory tract.