免疫原
Synthesized peptide derived from human Keratin 77
特异性
This antibody detects endogenous levels of human Keratin 77
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:50-200, WB 1:500-2000. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in the skin and eccrine sweat glands. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009],
功能
miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,PTM:Undergoes deimination of some arginine residues (citrullination).,similarity:Belongs to the intermediate filament family.,tissue specificity:Expressed exclusively in skin.,
基因名称（Gene Name）
KRT77 KRT1B
其他名称
Keratin, type II cytoskeletal 1b (Cytokeratin-1B;CK-1B;Keratin-77;K77;Type-II keratin Kb39)
细胞定位
cytoskeleton,intermediate filament,keratin filament,extracellular exosome,
组织表达
Expressed exclusively in skin.
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