免疫原
Synthesized peptide derived from human Secretogranin-1
特异性
This antibody detects endogenous levels of human Secretogranin-1
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:50-200, WB 1:500-2000. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009],
功能
function:Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.,PTM:Extensively processed by limited proteolysis at conserved basic residues. Alternative processing are seen in different tissues.,similarity:Belongs to the chromogranin/secretogranin protein family.,subcellular location:Neuroendocrine and endocrine secretory granules.,tissue specificity:Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver.,
基因名称(Gene Name)
CHGB SCG1
其他名称
Secretogranin-1 (Chromogranin-B;CgB;Secretogranin I;SgI) [Cleaved into: GAWK peptide; CCB peptide]
细胞定位
Secreted. Neuroendocrine and endocrine secretory granules.
组织表达
Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver.