免疫原
Synthetic peptide from human protein at AA range: 31-80
特异性
The antibody detects endogenous CDNF
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
CDNF (Cerebral Dopamine Neurotrophic Factor) is a Protein Coding gene. Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity).
基因名称(Gene Name)
CDNF ARMETL1
蛋白名称
Cerebral dopamine neurotrophic factor (ARMET-like protein 1) (Conserved dopamine neurotrophic factor)
其他名称
Cerebral dopamine neurotrophic factor (ARMET-like protein 1;Conserved dopamine neurotrophic factor)
组织表达
Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum.