免疫原
Synthetic peptide from human protein at AA range: 50-90
特异性
The antibody detects endogenous DDT
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
D-dopachrome tautomerase converts D-dopachrome into 5,6-dihydroxyindole. The DDT gene is related to the migration inhibitory factor (MIF) in terms of sequence, enzyme activity, and gene structure. DDT and MIF are closely linked on chromosome 22. [provided by RefSeq, Jul 2008],
功能
catalytic activity:D-dopachrome = 5,6-dihydroxyindole + CO(2).,function:Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI).,similarity:Belongs to the MIF family.,subunit:Homotrimer.,
蛋白名称
D-dopachrome decarboxylase (EC 4.1.1.84) (D-dopachrome tautomerase) (Phenylpyruvate tautomerase II)
其他名称
D-dopachrome decarboxylase (EC 4.1.1.84;D-dopachrome tautomerase;Phenylpyruvate tautomerase II)
组织表达
Highly expressed in the liver and at lower levels in the heart, lung and pancreas.