免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human PGLYRP1. AA range:131-180
特异性
PGLYRP1 Polyclonal Antibody detects endogenous levels of PGLYRP1 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
PGLYRP1 (Peptidoglycan Recognition Protein 1) is a Protein Coding gene. Among its related pathways are TNF Signaling (sino). GO annotations related to this gene include peptidoglycan binding and N-acetylmuramoyl-L-alanine amidase activity. An important paralog of this gene is PGLYRP4.
功能
peptidoglycan metabolic process, polysaccharide catabolic process, polysaccharide metabolic process, aminoglycan metabolic process, aminoglycan catabolic process, glycosaminoglycan catabolic process, defense response, immune response, behavior, rhythmic behavior, circadian rhythm, macromolecule catabolic process, peptidoglycan catabolic process, detection of external stimulus, detection of biotic stimulus, response to bacterium, detection of bacterium,carbohydrate catabolic process, circadian sleep/wake cycle process, glycosaminoglycan metabolic process, defense response to bacterium, circadian sleep/wake cycle, regulation of circadian sleep/wake cycle, regulation of circadian rhythm, innate immune response, regulation of circadian sleep/wake cycle, sleep, rhythmic process, circadian behavior,regulation of behavior, defense response to Gram-positive bacterium, detection of stimulus,
蛋白名称
Peptidoglycan recognition protein 1
其他名称
PGLYRP1; PGLYRP; PGRP; TNFSF3L; SBBI68; Peptidoglycan recognition protein 1; Peptidoglycan recognition protein short; PGRP-S
细胞定位
Secreted . Cytoplasmic granule .
组织表达
Highly expressed in bone marrow. Weak expression found in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils.