免疫原
Synthesized peptide derived from human BCLAF1 (Phospho-Ser531)
特异性
This antibody detects endogenous levels of BCLAF1 (Phospho-Ser531) at Human, Mouse,Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.208% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
功能
function:Death-promoting transcriptional repressor.,sequence caution:Contaminating sequence. Potential poly-A sequence.,subunit:Interacts with Bcl-2 related proteins, EMD, with the adenovirus E1B 19 kDa protein and with DNA.,tissue specificity:Ubiquitous.,
基因名称(Gene Name)
BCLAF1 BTF KIAA0164
蛋白名称
BCLAF1 (Phospho-Ser531)
其他名称
Bcl-2-associated transcription factor 1 (Btf)
细胞定位
Cytoplasm. Nucleus. Nucleus speckle . Nucleus, nucleoplasm .