免疫原
Synthesized peptide derived from human LTK/ALK (Phospho-Tyr672/Tyr1278)
特异性
This antibody detects endogenous levels of LTK/ALK (Phospho-Tyr672/Tyr1278) at Human, Mouse,Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.199% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
leukocyte receptor tyrosine kinase(LTK) Homo sapiens The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],
功能
alternative products:Additional isoforms seem to exist,catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:The exact function of this protein is not known. It is probably a receptor with a tyrosine-protein kinase activity.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in non-hematopoietic cell lines and T- and B-cell lines.,
蛋白名称
LTK/ALK (Phospho-Tyr672/Tyr1278)
其他名称
Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)
细胞定位
Cell membrane ; Single-pass type I membrane protein .
组织表达
Expressed in non-hematopoietic cell lines and T- and B-cell lines.