免疫原
Synthesized peptide derived from human CDX2 (Phospho-Ser283)
特异性
This antibody detects endogenous levels of CDX2 (Phospho-Ser283) at Human, Mouse,Rat
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.194% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012],
功能
function:Involved in the transciptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.,PTM:Phosphorylation of Ser-60 mediates the transactivation capacity.,similarity:Belongs to the Caudal homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
基因名称（Gene Name）
CDX2 CDX3
蛋白名称
CDX2 (Phospho-Ser283)
其他名称
Homeobox protein CDX-2 (CDX-3) (Caudal-type homeobox protein 2)
组织表达
Detected in small intestine, colon and pancreas.
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