免疫原
Synthesized phosho peptide around human MOB1 (Thr35)
特异性
This antibody detects endogenous levels of Human Mouse Rat MOB1 (phospho-Thr35)
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
The protein encoded by this gene is a component of the Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],
功能
function:Stimulates the kinase activity of STK38 and STK38L.,PTM:Phosphorylated.,similarity:Belongs to the MOB1/phocein family.,subunit:Binds STK38 and STK38L.,
其他名称
MOB kinase activator 1A (Mob1 alpha) (Mob1A) (Mob1 homolog 1B) (Mps one binder kinase activator-like 1B)
Fields
>>Hippo signaling pathway;>>Hippo signaling pathway - multiple species
细胞定位
cytosol,extracellular exosome,
组织表达
Adrenal gland, bone marrow, brain, placenta, prostate, salivary gland, skeletal muscle, testis, thymus, thyroid gland, heart, spinal cord, fetal brain and fetal liver.
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