免疫原
Synthesized peptide derived from human MAP2 (Phospho-Thr1616)
特异性
This antibody detects endogenous phospho levels of MAP2 (Phospho-Thr1616) at Human:T1616, Mouse:T1620, Rat:T1622
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:50-200, WB 1:500-2000. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010],
功能
alternative products:Additional isoforms seem to exist,function:The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.,PTM:MAP2A/c is phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 3 Tau/MAP repeats.,similarity:Contains 4 Tau/MAP repeats.,
蛋白名称
MAP2 (Phospho-Thr1616)
其他名称
Microtubule-associated protein 2 (MAP-2)
细胞定位
Cytoplasm, cytoskeleton . Cell projection, dendrite .
组织表达
Brain,Brain cortex,Epithelium,Pancreas,Testis,
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