免疫原
Recombinant Protein of ATG13
特异性
The antibody detects endogenous ATG13 protein
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:50-300. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
The protein encoded by this gene is an autophagy factor and a target of the TOR kinase signaling pathway. The encoded protein is essential for autophagosome formation and mitophagy. [provided by RefSeq, Oct 2016],
功能
autophagic vacuole formation, autophagy, vacuole organization, cellular response to starvation, response to extracellular stimulus, macroautophagy, response to nutrient levels, cellular response to extracellular stimulus, cellular response to nutrient levels, cellular response to stress, response to starvation,
基因名称(Gene Name)
ATG13 KIAA0652
蛋白名称
Autophagy-related protein 13
其他名称
Autophagy-related protein 13
Fields
>>Autophagy - other;>>Autophagy - animal;>>Longevity regulating pathway;>>Alzheimer disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Spinocerebellar ataxia;>>Pathways of neurodegeneration - multiple diseases
细胞定位
Cytoplasm, cytosol . Preautophagosomal structure . Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. .