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MEFV rabbit pAb

说明书

BYab-10227

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB
分子量(DA)
免疫原
Synthesized peptide derived from human MEFV AA range: 517-567
特异性
This antibody detects endogenous levels of human MEFV
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:1000-2000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度
1 mg/ml
背景(Background)
功能
基因名称(Gene Name)
MEFV MEF
蛋白名称
Pyrin (Marenostrin)
简称
MEFV
其他名称
Fields
>>NOD-like receptor signaling pathway;>>Yersinia infection
人基因ID
4210
人蛋白质序列数据库
O15553
小鼠基因ID
54483
小鼠蛋白质序列数据库
Q9JJ26
大鼠基因ID
54483
大鼠蛋白质序列数据库
Q9JJ25
细胞定位
[Isoform 1]: Cytoplasm, cytoskeleton . Cell projection, ruffle . Cell projection, lamellipodium . Nucleus . Cytoplasm . Cytoplasmic vesicle, autophagosome . Associated with microtubules and with the filamentous actin of perinuclear filaments and peripheral lamellar ruffles (PubMed:11468188). In pre-apoptotic cells, colocalizes with PYCARD/ASC in large specks (inflammasomes) (PubMed:11468188). In migrating monocytes, strongly polarized at the leading edge of the cell where it colocalizes with polymerizing actin and PYCARD/ASC (PubMed:11468188). .; [Isoform 2]: Nucleus .
组织表达
Expressed in peripheral blood leukocytes, particularly in mature granulocytes and to a lesser extent in monocytes but not in lymphocytes. Detected in spleen, lung and muscle, probably as a result of leukocyte infiltration in these tissues. Not expressed in thymus, prostate, testis, ovary, small intestine, colon, heart, brain, placenta, liver, kidney, pancreas. Expression detected in several myeloid leukemic, colon cancer, and prostate cancer cell lines.
储存(Storage)
-20°C/1 year

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MEFV rabbit pAb

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