免疫原
Synthesized peptide derived from human SETD8 AA range: 282-332
特异性
This antibody detects endogenous levels of human SETD8
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
基因名称(Gene Name)
SETD8 KMT5A PRSET7 SET07 SET8
蛋白名称
N-lysine methyltransferase SETD8 (EC 2.1.1.-) (H4-K20-HMTase SETD8) (Histone-lysine N-methyltransferase SETD8) (EC 2.1.1.43) (Lysine N-methyltransferase 5A) (PR/SET domain-containing protein 07) (PR-S
Fields
>>Lysine degradation;>>Metabolic pathways
细胞定位
Nucleus. Chromosome. Specifically localizes to mitotic chromosomes. Colocalized with SIRT2 at mitotic foci. Associates with chromosomes during mitosis; association is increased in a H(2)O(2)-induced oxidative stress-dependent manner. Associates with silent chromatin on euchromatic arms. Not associated with constitutive heterochromatin.