免疫原
Synthesized peptide derived from human RIF1 AA range: 1428-1478
特异性
This antibody detects endogenous levels of human RIF1
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
蛋白名称
Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog)
Fields
>>Signaling pathways regulating pluripotency of stem cells
细胞定位
Nucleus . Chromosome . Chromosome, telomere . Cytoplasm, cytoskeleton, spindle . Following interaction with TP53BP1, recruited to sites of DNA damage, such as DSBs (By similarity). Exhibits ATM- and TP53BP1-dependent localization to uncapped or aberrant telomeres and to DNA double strand breaks (DSBs) (PubMed:15342490). Does not associate with normal telomere structures (PubMed:15342490, PubMed:15583028). Localizes to microtubules of the midzone of the mitotic spindle during anaphase, and to condensed chromosomes in telophase (PubMed:15583028). .
组织表达
Highly expressed in testis.
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