免疫原
Synthesized peptide derived from human PRUNE AA range: 48-98
特异性
This antibody detects endogenous levels of human PRUNE
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
蛋白名称
Protein prune homolog (hPrune) (EC 3.6.1.1) (Drosophila-related expressed sequence 17) (DRES-17) (DRES17) (HTcD37)
Fields
>>Purine metabolism;>>Metabolic pathways
细胞定位
Cytoplasm. Nucleus. Cell junction, focal adhesion. In some transfected cells a nuclear staining is also observed.
组织表达
Ubiquitously expressed. Seems to be overexpressed in aggressive sarcoma subtypes, such as leiomyosarcomas and malignant fibrous histiocytomas (MFH) as well as in the less malignant liposarcomas.