免疫原
Synthesized peptide derived from human PHF11 AA range: 232-282
特异性
This antibody detects endogenous levels of PHF11 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene encodes a protein containing a PHD (plant homeodomain) type zinc finger. This gene has been identified in some studies as a candidate gene for asthma. Naturally-occurring readthrough transcription may occur from the upstream SETDB2 (SET domain bifurcated 2) gene to this locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
功能
alternative products:A number of isoforms may be produced,polymorphism:Variation in PHF11 seems to be associated with propensity to atopy and asthma.,similarity:Contains 1 PHD-type zinc finger.,subunit:Interacts with BRCA1.,tissue specificity:Expressed in all normal tissues tested, including lung, testis, small intestine, breast, liver and placenta.,
基因名称(Gene Name)
PHF11 BCAP
组织表达
Highly expressed in T and B-cells, as well as natural killer and mature dendritic cells. Expressed at higher levels in Th1 as compared to Th2 cells. Expressed at low levels in all normal tissues tested, including lung, testis, small intestine, breast, liver and placenta.