免疫原
Synthesized peptide derived from human WFKN2 AA range: 506-556
特异性
This antibody detects endogenous levels of WFKN2 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. This gene encodes a WFIKKN1-related protein which has the same domain organization as the WFIKKN1 protein. The WAP-type, follistatin type, Kunitz-type, and NTR-type protease inhibitory domains may control the action of multiple types of proteases. [provided by RefSeq, Jul 2008],
功能
function:Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin.,similarity:Belongs to the WFIKKN family.,similarity:Contains 1 BPTI/Kunitz inhibitor domain.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Kazal-like domain.,similarity:Contains 1 NTR domain.,similarity:Contains 1 WAP domain.,similarity:Contains 2 BPTI/Kunitz inhibitor domains.,subunit:Interacts with both mature and propeptide myostatin/MSTN.,tissue specificity:Primarily expressed in ovary, testis and brain, but not in liver. In fetal tissues, it is primarily expressed in brain, skeletal muscle, thymus and kidney.,
基因名称(Gene Name)
WFIKKN2 GASP1 WFIKKNRP UNQ9235/PRO31996
组织表达
Primarily expressed in ovary, testis and brain, but not in liver. In fetal tissues, it is primarily expressed in brain, skeletal muscle, thymus and kidney.