免疫原
Synthesized peptide derived from human GLTL5 AA range: 79-129
特异性
This antibody detects endogenous levels of GLTL5 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
caution:In contrast to other members of the family, it lacks the C-terminal ricin B-type lectin domain, which contributes to the glycopeptide specificity. Its precise function is therefore unsure.,cofactor:Calcium.,cofactor:Manganese.,domain:There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.,function:May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.,online information:GlycoGene database,online information:Putative polypeptide N-acetylgalactosaminyltransferase-like protein
基因名称(Gene Name)
GALNTL5 GALNT15
Fields
>>Mucin type O-glycan biosynthesis;>>Other types of O-glycan biosynthesis;>>Metabolic pathways
细胞定位
Late endosome membrane ; Single-pass type II membrane protein . Localizes to the juxtanuclear region, possibly the late endosome. Not localized in the Golgi apparatus in round spermatids (By similarity). .
组织表达
Mainly expressed in testis. Weakly or not expressed in other tissues.