免疫原
Synthesized peptide derived from human TSG10 AA range: 412-462
特异性
This antibody detects endogenous levels of TSG10 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:May play a role in the sperm tail fibrous sheath, a major sperm tail structure.,PTM:Appears to be processed in a 27 kDa and a 55 kDa peptide containing respectively the N-terminal and the C-terminal part of the precursor.,similarity:Belongs to the CEP135/TSGA10 family.,subcellular location:The 27 kDa peptide associates with the fibrous sheath in mature spermatozoa and localizes to the principal piece of sperm tail while the 55 kDa peptide localizes to the midpiece.,tissue specificity:Testis specific.,
基因名称(Gene Name)
TSGA10 CEP4L
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . In mature spermatozoa, localizes to the centriole and midpiece (PubMed:28905369). The 27-kDa peptide associates with the fibrous sheath in mature spermatozoa and localizes to the principal piece of sperm tail, while the 55-kDa peptide localizes to the midpiece (By similarity). Detected in the cytoplasm of almost all spermatogonial cells within the seminiferous tubules (By similarity). .
组织表达
Expressed in the testis, in spermatozoa (at protein level) (PubMed:11179690, PubMed:28905369). Expressed in actively dividing fetal tissues, including sternum, intestine, limb, kidney and stomach (PubMed:14585816).