免疫原
Synthesized peptide derived from human UBXN1 AA range: 56-106
特异性
This antibody detects endogenous levels of UBXN1 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol. Involved in ubiquitin-proteasome systems.,similarity:Contains 1 UBA domain.,similarity:Contains 1 UBX domain.,subunit:Component of a complex required to couple retrotranslocation, ubiquitination and deglycosylation composed of NGLY1, SAKS1, AMFR, VCP and RAD23B. Interacts with HOMER2 (By similarity). Interacts directly with VCP. Binds polyubiquitin.,
基因名称(Gene Name)
UBXN1 SAKS1
Fields
>>Protein processing in endoplasmic reticulum