免疫原
Synthesized peptide derived from human TMX1 AA range: 223-273
特异性
This antibody detects endogenous levels of TMX1 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
TXNDC1 is a thioredoxin (TXN; see MIM 187700)-related protein with disulfide reductase activity (Matsuo et al., 2001 [PubMed 11152479]).[supplied by OMIM, Mar 2008],
功能
function:May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions.,similarity:Contains 1 thioredoxin domain.,subcellular location:Predominantly found in the endoplasmic reticulum.,tissue specificity:Ubiquitous. Highly expressed in kidney, liver, placenta and lung.,
基因名称(Gene Name)
TMX1 TMX TXNDC TXNDC1 PSEC0085 UNQ235/PRO268
细胞定位
Membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Predominantly found in the endoplasmic reticulum. .
组织表达
Ubiquitous. Highly expressed in kidney, liver, placenta and lung.