免疫原
Synthesized peptide derived from human ABTB1 AA range: 163-213
特异性
This antibody detects endogenous levels of ABTB1 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq, Mar 2010],
功能
function:May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes.,similarity:Contains 2 ANK repeats.,similarity:Contains 2 BTB (POZ) domains.,tissue specificity:Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart.,
基因名称(Gene Name)
ABTB1 BPOZ PP2259
组织表达
Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart.