免疫原
Synthesized peptide derived from human KIF15 AA range: 974-1024
特异性
This antibody detects endogenous levels of KIF15 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:Plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly.,similarity:Belongs to the kinesin-like protein family. KLP2 subfamily.,similarity:Contains 1 kinesin-motor domain.,subcellular location:Detected during the interphase in the cytoplasm as finely punctuate pattern and irregularly shaped dots. Detected during mitosis on the mitotic spindle. Colocalizes with TPX2 in mitosis. Localizes at the central spindle at anaphase (By similarity). Localizes at the sites of invaginating cell membranes, a position that corresponds to the location of the contractile actomyosin ring of dividing cells (By similarity). Colocalizes with actin in interphase (By similarity). Colocalizes in dendrites and in growth cone of axons with microtubules.,subunit:Interacts with MKI67 and TPX2.,tissue specificity:Expressed in testis, colon, tymus and in breast cancer.,
基因名称(Gene Name)
KIF15 KLP2 KNSL7
细胞定位
Cytoplasm. Cytoplasm, cytoskeleton, spindle. Detected during the interphase in the cytoplasm as finely punctuate pattern and irregularly shaped dots. Detected during mitosis on the mitotic spindle. Colocalizes with TPX2 in mitosis. Localizes at the central spindle at anaphase (By similarity). Localizes at the sites of invaginating cell membranes, a position that corresponds to the location of the contractile actomyosin ring of dividing cells (By similarity). Colocalizes with actin in interphase (By similarity). Colocalizes in dendrites and in growth cone of axons with microtubules (By similarity). .
组织表达
Expressed in testis, colon, thymus and in breast cancer.