免疫原
Synthesized peptide derived from human EXOC6 AA range: 610-660
特异性
This antibody detects endogenous levels of EXOC6 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
The protein encoded by this gene is highly similar to the Saccharomyces cerevisiae SEC15 gene product, which is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast. It is one of the components of a multiprotein complex required for exocytosis. The 5' portion of this gene and two neighboring cytochrome p450 genes are included in a deletion that results in an autosomal-dominant form of nonsyndromic optic nerve aplasia (ONA). Alternative splicing and the use of alternative promoters results in multiple transcript variants. A paralogous gene encoding a similar protein is present on chromosome 2. [provided by RefSeq, Jan 2016],
功能
function:Component of the exocyst complex involved in the docking of exocystic vesicles with fusion sites on the plasma membrane.,similarity:Belongs to the SEC15 family.,subunit:The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8. Interacts with CEP110.,
基因名称（Gene Name）
EXOC6 SEC15A SEC15L SEC15L1
细胞定位
Cytoplasm . Cytoplasm, perinuclear region . Cell projection, growth cone . Midbody, Midbody ring . Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation. Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214). .
联系我们
关注我们
您当前的位置： 
说明书
成功添加到购物车
