免疫原
Synthesized peptide derived from human GBG11 AA range: 1-50
特异性
This antibody detects endogenous levels of GBG11 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1：50-200. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
This gene is a member of the guanine nucleotide-binding protein (G protein) gamma family and encodes a lipid-anchored, cell membrane protein. As a member of the heterotrimeric G protein complex, this protein plays a role in this transmembrane signaling system. This protein is also subject to carboxyl-terminal processing. Decreased expression of this gene is associated with splenic marginal zone lymphomas. [provided by RefSeq, Jul 2008],
功能
function:Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.,similarity:Belongs to the G protein gamma family.,subunit:G proteins are composed of 3 units, alpha, beta and gamma. Interacts with beta-1 and beta-3, but not with beta-2.,tissue specificity:Abundantly expressed in all tissues tested except for brain.,
基因名称（Gene Name）
GNG11 GNGT11
Fields
>>Ras signaling pathway;>>Chemokine signaling pathway;>>PI3K-Akt signaling pathway;>>Apelin signaling pathway;>>Circadian entrainment;>>Retrograde endocannabinoid signaling;>>Glutamatergic synapse;>>Cholinergic synapse;>>Serotonergic synapse;>>GABAergic synapse;>>Dopaminergic synapse;>>Relaxin signaling pathway;>>Morphine addiction;>>Alcoholism;>>Human cytomegalovirus infection;>>Kaposi sarcoma-associated herpesvirus infection;>>Human immunodeficiency virus 1 infection;>>Pathways in cancer
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side .
组织表达
Abundantly expressed in all tissues tested except for brain.
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