免疫原
Synthesized peptide derived from human NUDT5 AA range: 95-145
特异性
This antibody detects endogenous levels of NUDT5 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013],
功能
catalytic activity:ADP-ribose + H(2)O = AMP + D-ribose 5-phosphate.,catalytic activity:ADP-sugar + H(2)O = AMP + alpha-D-aldose 5-phosphate.,cofactor:Magnesium.,function:Hydrolyzes with similar activities ADP-ribose, ADP-mannose, and ADP-glucose. Can also hydrolyze other nucleotide sugars with low activity.,similarity:Belongs to the Nudix hydrolase family.,subunit:Homodimer.,tissue specificity:Widely expressed. Most abundant in liver.,
基因名称（Gene Name）
NUDT5 HSPC115
Fields
>>Purine metabolism;>>Metabolic pathways
组织表达
Widely expressed. Most abundant in liver.
联系我们
关注我们
您当前的位置： 
说明书
成功添加到购物车
