免疫原
Synthesized peptide derived from human ADPRM AA range: 225-275
特异性
This antibody detects endogenous levels of ADPRM at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
catalytic activity:ADP-ribose + H(2)O = AMP + D-ribose 5-phosphate.,catalytic activity:CDP-choline + H(2)O = CMP + phosphocholine.,catalytic activity:CDP-glycerol + H(2)O = CMP + sn-glycerol 3-phosphate.,cofactor:Magnesium.,function:hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress.,similarity:Belongs to the ADPRibase-Mn family.,subunit:Monomer.,
基因名称(Gene Name)
ADPRM C17orf48 MDS006 Nbla03831
Fields
>>Purine metabolism;>>Glycerophospholipid metabolism;>>Metabolic pathways
细胞定位
cytosol,integral component of membrane,