免疫原
Synthesized peptide derived from human DSCR3 AA range: 163-213
特异性
This antibody detects endogenous levels of DSCR3 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008],
功能
similarity:Belongs to the VPS26 family.,tissue specificity:Ubiquitously expressed.,
基因名称(Gene Name)
DSCR3 DCRA DSCRA
组织表达
Ubiquitously expressed.