免疫原
Synthesized peptide derived from human FKB11 AA range: 58-108
特异性
This antibody detects endogenous levels of FKB11 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin (Rulten et al., 2006 [PubMed 16596453]).[supplied by OMIM, Mar 2008],
功能
catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,function:PPIases accelerate the folding of proteins during protein synthesis.,similarity:Belongs to the FKBP-type PPIase family.,similarity:Contains 1 PPIase FKBP-type domain.,
基因名称(Gene Name)
FKBP11 FKBP19 UNQ336/PRO535
细胞定位
Membrane ; Single-pass membrane protein .