免疫原
Synthesized peptide derived from human B3GN2 AA range: 190-240
特异性
This antibody detects endogenous levels of B3GN2 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2016],
功能
catalytic activity:UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R.,caution:Was indicated as B3Gal-T6 in submitted DNA entries.,cofactor:Manganese.,function:Can initiate the synthesis or the elongation of the linear poly-N-acetyllactosaminoglycans.,function:Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains.,online information:GlycoGene database,online information:N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase,online information:UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 31 family.,tissue specificity:In the adult, highly expressed in heart, brain, skeletal muscle and kidney and to a lesser extent in placenta
基因名称（Gene Name）
B3GNT2 B3GALT7 B3GNT1
Fields
>>Glycosaminoglycan biosynthesis - keratan sulfate;>>Glycosphingolipid biosynthesis - lacto and neolacto series;>>Metabolic pathways
细胞定位
Golgi apparatus membrane ; Single-pass type II membrane protein .
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