免疫原
Synthesized peptide derived from human CL16A AA range: 129-179
特异性
This antibody detects endogenous levels of CL16A at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene encodes a member of the C-type lectin domain containing family. Single nucleotide polymorphisms in introns of this gene have been associated with diabetes mellitus, multiple sclerosis and rheumatoid arthritis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],
功能
disease:Defects in CLEC16A might be a cause of insulin-dependent diabetes mellitus (IDDM) [MIM:222100].,similarity:Belongs to the CLEC16A/gop-1 family.,tissue specificity:Almost exclusively expressed in immune cells, including dendritic cells, B lymphocytes and natural killer cells.,
基因名称(Gene Name)
CLEC16A KIAA0350
细胞定位
Endosome membrane ; Peripheral membrane protein . Lysosome membrane ; Peripheral membrane protein . Associates with the endolysosome membrane. .
组织表达
Almost exclusively expressed in immune cells, including dendritic cells, B-lymphocytes and natural killer cells.