免疫原
Synthesized peptide derived from human OZF AA range: 3-53
特异性
This antibody detects endogenous levels of OZF at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
miscellaneous:Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpresseed in 80% of colorectal cancers.,PTM:Sumoylated.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 10 C2H2-type zinc fingers.,subunit:Binds DNA. Interacts with SUMO conjugating enzyme UBC9/UBE2I. Interacts with the telomeric protein TERF2IP.,tissue specificity:Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney.,
基因名称(Gene Name)
ZNF146 OZF
组织表达
Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpressed in 80% of colorectal cancers.