免疫原
Synthesized peptide derived from human VATO AA range: 149-199
特异性
This antibody detects endogenous levels of VATO at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
This gene encodes a portion of the V0 domain of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Activity of this enzyme is necessary for such varied processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014],
功能
function:Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.,similarity:Belongs to the V-ATPase proteolipid subunit family.,tissue specificity:Ubiquitous.,
基因名称（Gene Name）
ATP6V0B ATP6F
Fields
>>Oxidative phosphorylation;>>Metabolic pathways;>>Lysosome;>>Phagosome;>>Synaptic vesicle cycle;>>Vibrio cholerae infection;>>Epithelial cell signaling in Helicobacter pylori infection;>>Tuberculosis;>>Human papillomavirus infection;>>Rheumatoid arthritis
细胞定位
Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Multi-pass membrane protein .
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