免疫原
Synthesized peptide derived from human S7A14 AA range: 50-100
特异性
This antibody detects endogenous levels of S7A14 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.341% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene is predicted to encode a glycosylated, cationic amino acid transporter protein with 14 transmembrane domains. This gene is primarily expressed in skin fibroblasts, neural tissue, and primary endothelial cells and its protein is predicted to mediate lysosomal uptake of cationic amino acids. Mutations in this gene are associated with autosomal recessive retinitis pigmentosa. In mice, this gene is expressed in the photoreceptor layer of the retina where its expression increases over the course of retinal development and persists in the mature retina. [provided by RefSeq, Apr 2014],
功能
sequence caution:Translated as Glu.,similarity:Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.,
基因名称(Gene Name)
SLC7A14 KIAA1613
其他名称
Probable cationic amino acid transporter (Solute carrier family 7 member 14)
细胞定位
Lysosome membrane ; Multi-pass membrane protein . Exhibits a punctated pattern in the cytoplasm, which partially ovelaps with lysosomes.
组织表达
Expressed in skin fibroblasts.