免疫原
Synthesized peptide derived from human LRFN1 AA range: 529-579
特异性
This antibody detects endogenous levels of LRFN1 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.339% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:Involved in the regulation of excitatory synapses.,PTM:Glycosylated.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the LRFN family.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 7 LRR (leucine-rich) repeats.,subunit:Interacts with DLG1, DLGAP1, AMPA receptors and NMDA receptors (By similarity). Interacts with DLG4.,
基因名称(Gene Name)
LRFN1 KIAA1484 SALM2
其他名称
Leucine-rich repeat and fibronectin type III domain-containing protein 1 (Synaptic adhesion-like molecule 2)
细胞定位
Membrane ; Single-pass type I membrane protein . Cell junction, synapse . Cell junction, synapse, postsynaptic density membrane . Detected in excitatory, but not inhibitory, synaptic plasma membrane. .