免疫原
Synthesized peptide derived from human SEM4F AA range: 85-135
特异性
This antibody detects endogenous levels of SEM4F at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.336% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene encodes a transmembrane class IV semaphorin family protein, which plays a role in neural development. This gene may be involved in neurogenesis in prostate cancer, the development of neurofibromas, and breast cancer tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012],
功能
function:Has growth cone collapse activity against retinal ganglion-cell axons.,similarity:Belongs to the semaphorin family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 PSI domain.,similarity:Contains 1 Sema domain.,
基因名称(Gene Name)
SEMA4F SEMAM SEMAW
其他名称
Semaphorin-4F (Semaphorin-M) (Sema M) (Semaphorin-W) (Sema W)
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse, postsynaptic density . Perikaryon . Cell projection, dendrite . Colocalizes with DLG4 at synapses. .
组织表达
Amygdala,Brain,Liver,