免疫原
Synthesized peptide derived from human CE112 AA range: 475-525
特异性
This antibody detects endogenous levels of CE112 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.234% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene encodes a coiled-coil domain containing protein that belongs to the cell division control protein 42 effector protein family. In neurons, it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression. In addition, the protein has been identified as a component of the human centrosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014],
功能
sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 563.,
基因名称(Gene Name)
CEP112 CCDC46
其他名称
Centrosomal protein of 112 kDa (Coiled-coil domain-containing protein 46)
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Localizes around spindle poles in some cells. .
组织表达
Lung,PCR rescued clones,Testis,Uterus,