免疫原
Synthesized peptide derived from human PRS55 AA range: 173-223
特异性
This antibody detects endogenous levels of PRS55 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.24% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene encodes a member of a group of membrane-anchored chymotrypsin (S1)-like serine proteases. The enocoded protein is primarily expressed in the Leydig and Sertoli cells of the testis and may be involved in male fertility. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010],
功能
function:Probable serine protease.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,
基因名称(Gene Name)
PRSS55 UNQ9391/PRO34284
其他名称
Serine protease 55 (EC 3.4.21.-)
细胞定位
[Isoform 1]: Cell membrane ; Lipid-anchor, GPI-anchor . Cytoplasm, cytosol . Mainly found in the membrane part of the cells and only in small amounts in the cytosol. .; [Isoform 2]: Cytoplasm, cytosol . Present primarily in the cytosol and only in minor amounts in the membrane fraction. .
组织表达
Only detected in testis. Expressed in spermatogonia, spermatocytes, spermatids, Leydig and Sertoli cells. Expressed in prostate cancer and ovarian cancer (at protein level).